A missile strike on a mail depot in the eastern Ukrainian city of Kharkiv has killed six people and injured 16 others, officials said on Sunday. The blast was caused by a Russian S-300 rocket, Kharkiv governor Oleh Syniehubov said in a post on the Telegram messaging app. All of the victims were employees of private Ukrainian postal and courier service Nova Poshta. In a statement, the company said the air raid siren had sounded just moments before the attack, leaving those inside the depot with no time to reach shelter. It announced that Sunday would be a day of mourning for the firm. Ukrainian president Volodymyr Zelensky posted a video showing the building with destroyed windows and construction materials strewn across the floor. He described the strike as an attack on an “ordinary civilian object”. “We need to respond to Russian terror every day with results on the front line. And, even more so, we need to strengthen global unity in order to fight against this terror,” he wrote on social media. “Russia will not be able to achieve anything through terror and murder. The end result for all terrorists is the same: the need to face responsibility for what they have done.” Elsewhere in the Kharkiv region, three people were injured in Russian shelling on the city of Kupiansk, Mr Syniehubov said. The Ukrainian-held frontline city has been at the heart of fierce fighting as both Moscow and Kyiv push for battlefield breakthroughs amid the looming onset of wintry conditions. Officials in southern Ukraine said on Sunday that the Russian military had used a record number of aerial bombs over the country’s Kherson region in the past 24 hours. Natalia Humeniuk, a spokeswoman for the Ukrainian military’s Operational Command South, said 36 missiles had been recorded over the area, with some villages being hit by several strikes. It comes as further south in the east, Ukraine has been trying to stop a new push by Russian forces to gain more territory there, amid Kyiv’s gruelling counteroffensive that has continued for months. Moscow’s drive to capture the town of Avdiivka encountered fierce resistance on Saturday, Ukraine’s military said, with defences bolstered by fortifications erected nearly a decade ago. “The enemy is becoming more active, but is incurring heavy losses,” General Oleksandr Tarnavskyi, commander of Ukraine’s troops in the south, said on Telegram. Russia’s Defence Ministry, in its evening report, made no mention of Avdiivka, but reported strikes on areas outside Bakhmut, a town seized by Moscow’s forces in May after months of battles. Both towns are in the eastern Donetsk region. Avdiivka has withstood enemy attacks for months. Video footage shows buildings in ruins and streets barely distinguishable. The town was briefly captured in 2014 by Russian-backed separatists who seized large swathes of eastern Ukraine, but was retaken by Ukrainian forces who built solid fortifications. The Institute for the Study of War, a US think-tank, said Russian troops had “marginally advanced” near Avdiivka. Additional reporting by agencies Read More Aftermath of Russian missile strike on Ukraine mail depot that killed six Ukrainian officials say civilians were killed and wounded in Russian overnight attacks Russian attacks kill six in Ukraine as Kyiv ramps up drone counterstrikes NATO member Romania finds more drone fragments on its soil after Russian again hits southern Ukraine Russia claims `neo-Nazis' were at wake for Ukrainian soldier in village struck by missile killing 52 ‘Six killed in Kharkiv strike’ as Kherson sees ‘record’ bomb attacks - live

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A woman who was born with a rare inherited skin blistering disorder which caused her to get “bullied” and feel “like a freak” throughout her childhood and teenage years, as well as forcing her onto a soft food diet of “bananas and custard” for weeks at a time, now writes inclusive children’s books with a focus on disability to encourage “other children to grow up with confidence”. Vie Portland, a 52-year-old confidence coach, author and speaker from Winchester, was born with epidermolysis bullosa simplex generalised intermediate but was not formally diagnosed with the skin condition until she was 28. According to the NHS, epidermolysis bullosa (EB) is a rare inherited skin disorder that causes the skin to become very fragile, and any trauma or friction to the skin can cause painful blisters. Vie is yet to find a treatment that helps her condition, and her feet are regularly covered with huge internal blisters which feel like she has “stones under (her) skin.” Her condition even means that she cannot eat “anything acidic or too peppery” and often spends weeks eating “just bananas and custard”. She has also developed thoracic outlet syndrome, chronic bursitis, and often has spasms, because of walking with a limp to try to ease the pain. Now, Vie writes inclusive children’s books to raise awareness about living with a disability, because she grew up “afraid that there was no one else like (her)”, and hopes to write a book about someone with her condition next. Vie told PA Real Life: “So it feels like I’ve got stones under my skin all the time on my feet and it doesn’t matter how much you try to explain that to someone people just don’t get it. “Even things like if I meet friends for a drink in a lovely pub garden – I’ll be in agony because of walking on gravel and it takes so much energy out of me. “I can’t eat anything acidic or too peppery – sometimes I have to eat just bananas and custard for weeks.” Vie was born with the skin condition, saying: “I was born with no skin on my bottom and had some skin missing on my left foot. “The charity that works with people that have EB wasn’t around then – I spoke to someone recently from Debra, the charity, and they said if you looked at all the people on a double-decker bus, you’d expect to find at least one person with psoriasis. “But, you’d have to wait for over 700 buses before you met someone with EB.” As a child, Vie regularly had huge blisters all over her feet and the back of her heels. She explained: “I remember wearing jelly shoes one summer, and heat and friction are two of my triggers. “Throughout the day, blisters grew around the rubber shoes and I had to have the pair of shoes cut off my feet – it was excruciating.” When Vie was a teenager, she was very self-conscious of her condition, she explained: “I was in constant pain, and I struggled with all shoes and walking anywhere. “We’re always told not to pop blisters, but when you have EB they tell you to pop them because they get so big. “I didn’t know that at the time and it was just so painful. “People were noticing how I walk and I was embarrassed to show my feet – I didn’t have a normal childhood because of this. “Even something as simple as opening a bottle makes several layers of skin come off and cause me to have raw skin all over my hands, I was told this was weird by other people.” Doctors were baffled by Vie’s condition, over the years, she was told she had different types of eczema and even that she was allergic to her own sweat. But, at age 28, she was diagnosed with EB by a dermatologist in London. She said: “I just grew up believing that it was my fault and I was afraid that there was no one else like me.” “It all just made sense. “They even took pictures of my feet for a medical journal because it was so rare.” After getting her diagnosis, Vie began researching the charity DEBRA, which specialises in EB. She said: “I started finding out that there were people like me – it was amazing, growing up, I was bullied and felt like a freak.” Since then, Vie has sadly not been able to find a treatment that helps her condition. “There’s no cure for EB but things have moved on a lot over the past 20 years,” she said. “We have special types of dressings and creams which can help alleviate the pain.” On top of this, because Vie has been walking “unusually” for most of her life, she has developed thoracic outlet syndrome, chronic bursitis, and often has spasms. Vie said: “It can be frustrating at times because it just feels like no one will ever understand what it is like. “For most people, blisters are a bit painful, but it’s all right, but for me, it’s one of the worst pains in the world.” Now, Vie is focussing on raising awareness about living with a disability, and has recently written two inclusive children’s books called ‘Where Are We Going?’ and ‘Who Am I?’. She said: “I want other children to grow up with confidence and not to feel like a freak like me. “Children aren’t born with prejudice and I think it’s really important to teach them about all of our amazing cultures and worlds. “In my books, I don’t explicitly say the character is disabled until the discussion questions at the end – I want the character to be accepted and not defined by their disability. “I think people have more in common with each other than things that are different, and that’s a beautiful thing. “I’m hoping to write a book about someone with my condition – that’s my next plan.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Fraser Franks undergoing heart surgery – four years after ‘hidden’ condition cut short football career 4 viral TikTok make-up trends you’ll actually want to try Childhood Cancer Awareness Month: What are the warning signs that your child might have cancer?

Former president Donald Trump took credit for the end of abortion rights enshrined under Roe v Wade, which was overturned by the US Supreme Court a year ago. Mr Trump spoke at the Faith & Freedom Coalition’s Road to Majority Conference on the first anniversary of the Supreme Court’s Dobbs v Jackson Women’s Health decision. The crowd gave Mr Trump a standing ovation when he referenced the ruling, a long-sought policy outcome of the religious right. “Exactly one year ago today, those justices were the pivotal votes in the Supreme Court’s landmark decision ending the constitutional atrocity known as Roe v Wade,” he said. The twice-indicted and twice-impeached former president said that what differentiated him from other presidential candidates who attended the conference was that he actually facilitated the end of the enshrined right to seek an abortion, which had been the law of the land for half a century. “Conservatives had been trying for 50 years, exactly 50 years,” he said. The former president gave the closing address at the conference which featured every other Republican presidential candidate, including Florida Gov Ron DeSantis, businessman Vivek Ramaswamy, former vice president Mike Pence, former New Jersey governor Chris Christie, former South Carolina governor Nikki Haley, former Arkansas governor Asa Hutchinson and Sen Tim Scott (R-SC). But the former president received the largest applause of any of the candidates, even noting how attendees booed Mr Christie, who has staged a longshot candidacy for president largely to criticise Mr Trump. Many Republicans have feared that the end of Roe v Wade cost Republicans otherwise winnable elections during the 2022 midterms. Indeed a survey from NBC News found that 61 per cent of voters disapproved of the Dobbs decision. Mr Trump made his typical attacks on the so-called “radical left”. “We cannot be afraid to take on the Democratic extremists,” he said. “We have to be strong and powerful. That’s why when I’m re-elected I will continue to fight against the demented late-term abortionist and the Democrat Party who believe in unlimited abortion on demand and even executing babies after birth.” Mr Trump said he would support exceptions for rape, incest and the life of the mother. The former president also said that he would seek a federal role on abortion. But the former president did not articulate what federal restrictions he would support. By contrast, Mr Pence, his former vice president, announced his support for a 15-week national abortion ban. “Some have even gone on to blame the overturning of Roe v Wade for election losses in 2022,” Mr Pence said in his address on Friday. “But let me say from my heart, the cause of life is the calling of our time and we must not rest and must not relent until we restore the sanctity of life to the center of American law in every state in this country.” Mr Trump has long boasted of how he got three conservative Supreme Court justices on the bench, which paved the way to the end of federal abortion rights. But Mr Trump has also criticised his Republican rivals for being too harsh when it comes to reproductive freedom. Mr Trump for his part cited numerous policy strides he made on abortion despite the fact that he spent many years as a Democrat who supported abortion rights. In addition, the former president said he would support measures to promote adoption. “I will ask Congress to expand the adoption tax credit,” he said. “We’ll do that because a lot of people have been adopting and that’s a great thing.” But Mr Trump received even louder applause when he spoke about restricting transgender girls from participating in girls’ sports. Numerous Republican legislatures and governors, including Mr DeSantis, have passed and signed legislation both restricting transgender girls’ participation in women’s sports and restricting gender-affirming care for minors. “I will sign into law prohibiting child sexual mutilation in all 50 states,” he said. “And on day one, I will reinstate the Trump ban on transgenders in the military.” He also went further and said that the federal government would not support gender transition care. Despite recently being indicted, the former president received numerous applause when he brought up the slew of legal investigations and the recent charges against him. Mr Trump had pleaded not guilty to both criminal indictments against him. “Every time the radical left Democrats, Marxists communists and fascists indict me, I consider it a great badge of courage,” he said. The former president event attempted to argue that he was a martyr for the evangelical audience. “I’m getting indicted for you,” he told the crowd. Read More Chris Christie defiant as conservative crowd boos Trump criticism Trump news – live: Trump takes credit for Roe downfall as he rambles about Russia’s ‘big mess’ One year later, the Supreme Court's abortion decision is both scorned and praised Biden warns Republicans aren’t done with abortion bans as protesters hit streets on anniversary of Roe’s fall One year later, the Supreme Court's abortion decision is both scorned and praised The religious right used to be uneasy about Trump – but his dominance is now complete